BENZOCAINE URETHANE SOLUTION IN OPHTHALMOLOGY

Benzocaine-Induced Cyanosis

Figure 2. A chest x-ray showing correct endotra-cheal tube placement and no acute lung pathology. DESCRIPTION A 28-year-old woman underwent fiberoptic intubation for incision and drainage of joint space infection of a temporomandibular joint arthroplasty performed 10 days prior. The airway was prepared with 4 sprays of topical benzocaine spray and 3% lidocaine ointment. After 30 minutes, the pe...

Tuberculin in Ophthalmology Tuberculin in Ophthalmology

Benzocaine-induced methemoglobinemia.

A case is reported in which a patient developed methemoglobinemia-induced cyanosis while under general anesthesia during surgery for multiple fascial space infections. The cause of methemoglobinemia was 20% benzocaine spray used for local anesthesia before intubation. Acutely developing methemoglobinemia is infrequently encountered in clinical practice. When confronted with cyanosis in the abse...

Poison Control Center Management of Benzocaine Exposures

Benzocaine is a topical anesthetic frequently used in healthcare facilities and in over-the-counter medications in concentrations up to 20%. Benzocaine may induce methemoglobinemia, a condition that impairs the blood’s ability to carry oxygen. The optimal management of exposure to benzocaine remains unclear because serious toxicity is uncommon and may not be dose-related. In 2000, it was estima...

Urethane therapy in leukemia.

T HE purpose of this paper is to report the results of urethane therapy of the leukemias, based on a study of 2.4 patients. In April, 1946, Haddow and Sexton’ described the influence of various carbamic esters on experimental rat cancers. Ethyl carbamate (urethane) yielded the best results. It alone produced inhibition of tumor growth and fibrous replacement of the cancerous rat tissue. For thi...